Label-free detection and size estimation of combustion-derived carbonaceous particles in a microfluidic approach.

ABSTRACT: Detection and size estimation of combustion-derived carbonaceous particles (CDCPs) are important to understand their toxicity. Size determination of individual nano- and microparticles (NMPs) based on scattered light is a straightforward method. However, detection and sizing of CDCPs in biological samples based on scattering alone are not possible due to the compositional heterogeneity of NMPs present in biological samples. Label-free identification of CDCPs based on unique white light (WL) emission, using femtosecond (fs) pulsed near-infrared (NIR) lasers, has emerged as a reliable method even in complex biological samples. However, size estimation of CDCPs in biological samples using label-free techniques is still lacking. Here we report the development of a dual-channel multiphoton flow

SUBMITTER: Aslam I 

PROVIDER: S-EPMC9419628 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature