Dataset Information

The Role of Clinical Pharmacist in Pediatrics' Adherence to Antiepileptic Drugs.

ABSTRACT:

Background

Rate of nonadherence to antiepileptic drugs (AEDs) in children is about 33%. Engaging clinical pharmacists in the management of patients has proved to increase adherence to medications which will improve the outcomes of treatment.

Objectives

To investigate the effect of a clinical pharmacist-led education on the adherence to AEDs in pediatric patients with epilepsy. Secondary outcomes include effectiveness and safety of AEDs, satisfaction with information about AEDs provided to the caregivers, and patients quality of life (QoL).

Methods

This was an interventional study where pediatric patients were randomly assigned to the intervention (n = 41) or the control (n = 40) group. A 30-minute clinical pharmacist-led educational interview to the parent/caregiver was provided to the first group as add-on to standard medical care received by latter. Outcomes were measured at baseline and after 8-week follow-up.

Results

The intervention group had an increase in mean adherence score from 6 ± 1.09 at baseline to 7.6 ± 0.9 at follow-up (P value < 0.001), while the control group had no significant change (P value > 0.05), the difference between the 2 groups at follow-up was significant (P value < 0.0001). No significant difference was observed between groups at follow-up with regard to effectiveness (P value > 0.05), and safety (P value = 0.08). While higher satisfaction with information (P value < 0.0001), and higher QoL (P value < 0.05) was observed in the intervention group.

Conclusion and relevance

Clinical pharmacist-led education had a positive outcome on pediatric patients with epilepsy with regard to adherence, effectiveness, safety, satisfaction with information about AEDs, and QoL.

SUBMITTER: Jarad S

PROVIDER: S-EPMC9420919 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

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Publications

The Role of Clinical Pharmacist in Pediatrics' Adherence to Antiepileptic Drugs.

Jarad Suha S Akour Amal A Khreisat Wael H WH Elshammari Afrah K AK Madae'en Saba S

The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians 20220719 5

<h4>Background</h4>Rate of nonadherence to antiepileptic drugs (AEDs) in children is about 33%. Engaging clinical pharmacists in the management of patients has proved to increase adherence to medications which will improve the outcomes of treatment.<h4>Objectives</h4>To investigate the effect of a clinical pharmacist-led education on the adherence to AEDs in pediatric patients with epilepsy. Secondary outcomes include effectiveness and safety of AEDs, satisfaction with information about AEDs pro ...[more]

PMID: 36046350

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Dataset Information

The Role of Clinical Pharmacist in Pediatrics' Adherence to Antiepileptic Drugs.

Background

Objectives

Methods

Results

Conclusion and relevance

Publications

The Role of Clinical Pharmacist in Pediatrics' Adherence to Antiepileptic Drugs.

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