Age group DNA methylation differences in lemon sharks (Negaprion brevirostris): Implications for future age estimation tools.

ABSTRACT: Age information is often non-existent for most shark populations due to a lack of measurable physiological and morphological traits that can be used to estimate age. Recently, epigenetic clocks have been found to accurately estimate age for mammals, birds, and fish. However, since these clocks rely, among other things, on the availability of reference genomes, their application is hampered in non-traditional model organisms lacking such molecular resources. The technique known as Methyl-Sensitive Amplified Polymorphism (MSAP) has emerged as a valid alternative for studying DNA methylation biomarkers when reference genome information is missing, and large numbers of samples need to be processed. Accordingly, the MSAP technique was used in the present study to characterize global DNA methyla

SUBMITTER: Beal AP 

PROVIDER: S-EPMC9425014 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature