A case report of refractory angina in a patient with diabetes and apical hypertrophic cardiomyopathy.

ABSTRACT:

Background

Using serial imaging over time, this case reviews the natural history of co-morbid Type two diabetes (T2D) and apical hypertrophic cardiomyopathy (HCM) and assesses the potential combined impact on myocardial structure and perfusion.

Case summary

A 59-year-old patient with concomitant T2D and an apical phenotype of HCM was seen over a 11-year period with a significant burden of anginal chest pain. Chest pain was refractory to anti-anginal medical therapy and persisted at on-going follow-up. Multi-modality imaging demonstrated significant deterioration in coronary microvascular function and increased myocardial scar burden despite unobstructed epicardial coronary arteries.

Discussion

Comorbidity with T2D and apical HCM resulted in a significant increase in m

SUBMITTER: Jex N 

PROVIDER: S-EPMC9425848 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature