The accuracy of four formulas for LDL-C calculation at the fasting and postprandial states.

ABSTRACT:

Background

Elevated level of low-density lipoprotein cholesterol (LDL-C) is concerned as one of the main risk factors for cardiovascular disease, in both the fasting and postprandial states. This study aimed to compare the measured LDL-C with LDL-C calculated by the Friedewald, Martin-Hopkins, Vujovic, and Sampson formulas, and establish which formula could provide the most reliable LDL-C results for Chinese subjects, especially at the postprandial state.

Methods

Twenty-six subjects were enrolled in this study. The blood samples were collected from all the subjects before and after taking a daily breakfast. The calculated LDL-C results were compared with LDL-C measured by the vertical auto profile method, at both the fasting and postprandial states. The percentage difference

SUBMITTER: Xu J 

PROVIDER: S-EPMC9433804 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature