Recommendations on the Appropriate Management of Steroids and Discharge Planning During and After Hospital Admission for Moderate-Severe Ulcerative Colitis: Results of a RAND Appropriateness Panel.

ABSTRACT:

Introduction

Limited guidance exists for the postdischarge care of patients with ulcerative colitis hospitalized for moderate-severe flares.

Methods

RAND methodology was used to establish appropriateness of inpatient and postdischarge steroid dosing, discharge criteria, follow-up, and postdischarge biologic or small molecule initiation. A literature review informed on the panel's voting, which occurred anonymously during 2 rounds before and after a moderated virtual session.

Results

Methylprednisolone 40-60 mg intravenous every 24 hours or hydrocortisone 100 mg intravenous 3 times daily is appropriate for inpatient management, with methylprednisolone 40 mg being appropriate if intolerant of higher doses. It is appropriate to discharge patients once rectal bleeding has

SUBMITTER: Dulai PS 

PROVIDER: S-EPMC9437635 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature