Development and Validation of a Kidney-Transplant Specific Measure of Treatment Burden.
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ABSTRACT: Background
Treatment burden refers to the work involved in managing one's health and its impact on well-being and has been associated with nonadherence in patients with chronic illnesses. No kidney transplant (KT)-specific measure of treatment burden exists. The aim of this study was to develop a KT-specific supplement to the Patient Experience with Treatment and Self-Management (PETS), a general measure of treatment burden.Methods
After drafting and pretesting KT-specific survey items, we conducted a cross-sectional survey study involving KT recipients from Mayo Clinic in Minnesota, Arizona, and Florida. Exploratory factor analysis (EFA) was used to identify domains for scaling the KT-specific supplement. Construct and known-groups validity were determined.Results
Survey respondents (n = 167) had a mean age of 61 years (range 22-86) and received a KT on average 4.0 years ago. Three KT-specific scales were identified (transplant function, self-management, adverse effects). Higher scores on the KT-specific scales were correlated with higher PETS treatment burden, worse physical and mental health, and lower self-efficacy (p < 0.0001). Patients taking more medications reported higher transplant self-management burden.Conclusions
We developed a KT-specific supplement to the PETS general measure of treatment burden. Scores may help providers identify recipients at risk for nonadherence.
SUBMITTER: Lorenz EC
PROVIDER: S-EPMC9440455 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature
Publications
Development and Validation of a Kidney-Transplant Specific Measure of Treatment Burden.
Lorenz Elizabeth C EC Petterson Tanya M TM Zaniletti Isabella I Lackore Kandace A KA Johnson Bradley K BK Mai Martin L ML Nair Sumi S SS Bentall Andrew J AJ Yost Kathleen J KJ Eton David T DT
BMC nephrology 20220903 1
<h4>Background</h4>Treatment burden refers to the work involved in managing one's health and its impact on well-being and has been associated with nonadherence in patients with chronic illnesses. No kidney transplant (KT)-specific measure of treatment burden exists. The aim of this study was to develop a KT-specific supplement to the Patient Experience with Treatment and Self-Management (PETS), a general measure of treatment burden.<h4>Methods</h4>After drafting and pretesting KT-specific survey ...[more]
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