Dataset Information

Clinical outcomes in Covishield (ChAdOx1) and Covaxin (BBV-152) vaccinated individuals hospitalized with the Delta variant (B.1.617.2).

ABSTRACT:

Background

: Covishield (ChAdOx) and Covaxin (BBV-152) are the mainstream vaccines used in India and a few other countries.

Objective

: To assess the clinical outcomes of hospitalized COVID-19 patients vaccinated with either Covishield or Covaxin.

Methods

: This is a prospective, single center, observational cohort study conducted between April and June 2021 that recruited 1,160 hospitalized COVID-19 patients. Severity of disease at admission and during hospitalization, requirement for intensive care unit (ICU) admission and ventilatory support, inflammatory markers (CRP, ferritin, lactate dehydrogenase, D-Dimer), neutralizing antibody levels and mortality were assessed in vaccinated and unvaccinated individuals.