Association between maternal smoking, gender, and cleft lip and palate.

ABSTRACT:

Introduction

Cleft lip and/or palate (CL/P) represent the most common congenital anomalies of the face.

Objective

To assess the relationship between maternal smoking, gender and CL/P.

Methods

This is an epidemiological cross-sectional study. We interviewed 1519 mothers divided into two groups:

Cases

mothers of children with CL/P (n=843) and

Controls

mothers of children without CL/P (n=676). All mothers were classified as smoker or non-smoker subjects during the first trimester of pregnancy. To determine an association among maternal smoking, gender, and CL/P, odds ratios were calculated and the adjustment was made by a logistic regression model.

Results

An association between maternal smoking and the presence of cleft was observed. There was also

SUBMITTER: Martelli DR 

PROVIDER: S-EPMC9449023 | biostudies-literature | 2015 Sep-Oct

REPOSITORIES: biostudies-literature