Preoperative imaging predicts change in bone mineral density after parathyroidectomy for primary hyperparathyroidism.

ABSTRACT:

Background

Bone Mineral Density (BMD) improves after parathyroidectomy (PTX), but data on factors that predict bone recovery are limited. No studies have evaluated if preoperative imaging findings are associated with postoperative change in BMD. We hypothesized that larger, metabolically active glands would be associated with greater increase in BMD after PTX.

Methods

Patients with primary hyperparathyroidism (PHPT) who underwent combined Tc-99m sestamibi and 4D-CT imaging prior to PTX and had pre- and post-operative dual-energy X-ray absorptiometry (DXA) at our institution were considered for inclusion. Retrospectively, data were collected from imaging studies on each parathyroid gland, including estimated weight (using the ellipsoid formula) and contrast enhancement on 4D-

SUBMITTER: Steinl GK 

PROVIDER: S-EPMC9450481 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature