Twenty-year Follow-up of Patients With Epidemic Glomerulonephritis due to Streptococcus zooepidemicus in Brazil.

ABSTRACT:

Introduction

Post-streptococcal glomerulonephritis (PSGN) has a good prognosis in children, but few studies have evaluated the long-term renal outcomes in adults with PSGN.

Methods

In a follow-up study, 47 predominantly adult patients with PSGN due to group C Streptococcus zooepidemicus were reassessed 20 years after an outbreak in Nova Serrana, Brazil. We evaluated clinical characteristics, renal outcomes, and the trajectory of the estimated glomerular filtration rate (eGFR) by the creatinine-based chronic kidney disease-epidemiology collaboration equation from 5 follow-up assessments. Logistic regression and mixed-effects regression were used in the analysis.

Results

After 20 years, the participants' mean age was 56.6±15.1 years. Thirty-four (72%) patients ha

SUBMITTER: Pinto SW 

PROVIDER: S-EPMC9458988 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature