Lateral prefrontal cortex is a hub for music production from structural rules to movements.

ABSTRACT: Complex sequential behaviors, such as speaking or playing music, entail flexible rule-based chaining of single acts. However, it remains unclear how the brain translates abstract structural rules into movements. We combined music production with multimodal neuroimaging to dissociate high-level structural and low-level motor planning. Pianists played novel musical chord sequences on a muted MR-compatible piano by imitating a model hand on screen. Chord sequences were manipulated in terms of musical harmony and context length to assess structural planning, and in terms of fingers used for playing to assess motor planning. A model of probabilistic sequence processing confirmed temporally extended dependencies between chords, as opposed to local dependencies between movements. Violations of st

SUBMITTER: Bianco R 

PROVIDER: S-EPMC9476625 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature