External validation of a prediction model for estimating fat mass in children and adolescents in 19 countries: individual participant data meta-analysis.

ABSTRACT:

Objective

To evaluate the performance of a UK based prediction model for estimating fat-free mass (and indirectly fat mass) in children and adolescents in non-UK settings.

Design

Individual participant data meta-analysis.

Setting

19 countries.

Participants

5693 children and adolescents (49.7% boys) aged 4 to 15 years with complete data on the predictors included in the UK based model (weight, height, age, sex, and ethnicity) and on the independently assessed outcome measure (fat-free mass determined by deuterium dilution assessment).

Main outcome measures

The outcome of the UK based prediction model was natural log transformed fat-free mass (lnFFM). Predictive performance statistics of R², calibration slope, calibration-in-the-large, and root

SUBMITTER: Hudda MT 

PROVIDER: S-EPMC9490487 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature