Cannabidiol and epilepsy in Brazil: a current review.

ABSTRACT:

Background

Cannabidiol (CBD) has become a promising therapeutic option in the treatment of epilepsy. Recent studies provide robust evidence that CBD is effective and safe. Limitations in current knowledge and regulatory issues still limit CBD use. CBD use regarding epilepsy types still lacks clear guidelines.

Objective

To critically review the main current pharmacological features and clinical issues regarding CBD use in epilepsy, to provide current regulatory background regarding CBD use in Brazil, and to suggest a practical CBD therapeutic guide in Brazil.

Methods

Non-systematic literature review (up to February 2022) of current concepts of CBD and epilepsy, including the authors' personal experience.

Results

Five pivotal trials have led to CBD approval as an

SUBMITTER: Oshiro CA 

PROVIDER: S-EPMC9491442 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature