Evaluation of antibiotic escalation in response to nurse-driven inpatient sepsis screen

ABSTRACT:

Objective:

To determine the frequency and predictors of antibiotic escalation in response to the inpatient sepsis screen at our institution.

Design:

Retrospective cohort study.

Setting:

Two affiliated academic medical centers in Los Angeles, California.

Patients:

Hospitalized patients aged 18 years and older who had their first positive sepsis screen between January 1, 2019, and December 31, 2019, on acute-care wards.

Methods:

We described the rate and etiology of antibiotic escalation, and we conducted multivariable regression analyses of predictors of antibiotic escalation.

Results:

Of the 576 cases with a positive sepsis screen, antibiotic escalation occurred in 131 cases (22.7%). New infection was the most documented etiology of esc

SUBMITTER: Furukawa D 

PROVIDER: S-EPMC9495422 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature