Ontology highlight
ABSTRACT: 
SUBMITTER: Karami Fath M
PROVIDER: S-EPMC9501259 | biostudies-literature | 2022 Sep
REPOSITORIES: biostudies-literature

Karami Fath Mohsen M Babakhaniyan Kimiya K Anjomrooz Mehran M Jalalifar Mohammadrasoul M Alizadeh Seyed Danial SD Pourghasem Zeinab Z Abbasi Oshagh Parisa P Azargoonjahromi Ali A Almasi Faezeh F Manzoor Hafza Zahira HZ Khalesi Bahman B Pourzardosht Navid N Khalili Saeed S Payandeh Zahra Z
Vaccines 20220902 9
Glioblastoma (GBM) is the most typical and aggressive form of primary brain tumor in adults, with a poor prognosis. Successful glioma treatment is hampered by ineffective medication distribution across the blood-brain barrier (BBB) and the emergence of drug resistance. Although a few FDA-approved multimodal treatments are available for glioblastoma, most patients still have poor prognoses. Targeting epigenetic variables, immunotherapy, gene therapy, and different vaccine- and peptide-based treat ...[more]