Geographical Differences in the Self-Reported Functional Impairment of People With Human Immunodeficiency Virus (HIV) and Associations With Cardiometabolic Risk.

ABSTRACT:

Background

We sought to explore multinational differences in functional status by global burden of disease (GBD) regions in the REPRIEVE cohort.

Methods

REPRIEVE is a prospective, double-blind, randomized, placebo-controlled, multicenter, phase III primary cardiovascular prevention study of pitavastatin calcium vs placebo among people with human immunodeficiency virus (HIV, PWH) ages 40-75 on antiretroviral therapy (ART). GBD super regions were defined using World Health Organization classifications. Participants were categorized by impairment on the Duke Activity Status Instrument (DASI: none, some, moderate, severe). Logistic regression models examined risk factors and GBD regions associated with functional impairment. The association between functional impairment and card

SUBMITTER: Erlandson KM 

PROVIDER: S-EPMC9525090 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature