Effect of direct stenting on microvascular dysfunction during percutaneous coronary intervention in acute myocardial infarction: a randomized pilot study.

ABSTRACT:

Objective

Whether direct stenting (DS) without predilatation during primary percutaneous coronary intervention (PPCI) reduces microvascular dysfunction in patients with ST-elevation myocardial infarction is unclear. We performed a randomized study to assess the effect of DS on microvascular reperfusion.

Methods

Seventy-two patients undergoing PPCI were randomly assigned to the DS or conventional stenting (CS) with predilatation groups. The primary endpoint was the post-PPCI index of microcirculatory resistance (IMR). We compared thrombolysis in myocardial infarction myocardial perfusion (TMP) grades, ST-segment resolution, and long-term clinical outcomes between the groups.

Results

Microvascular reperfusion parameters immediately after PPCI (e.g., the IMR, TMP grade,

SUBMITTER: Kim BG 

PROVIDER: S-EPMC9528029 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature