The Relationship between Rate and Volume of Intravenous Fluid Administration and Kidney Outcomes after Angiography.

ABSTRACT:

Background and objectives

Contrast-associated AKI may result in higher morbidity and mortality. Intravenous fluid administration remains the mainstay for prevention. There is a lack of consensus on the optimal administration strategy. We studied the association of periprocedure fluid administration with contrast-associated AKI, defined as an increase in serum creatinine of at least 25% or 0.5 mg/dl from baseline at 3-5 days after angiography, and 90-day need for dialysis, death, or a 50% increase in serum creatinine.

Design, setting, participants, & measurements

We conducted a secondary analysis of 4671 PRESERVE participants who underwent angiographic procedures. Although fluid type was randomized, strategy of administration was at the discretion of the clinician. We divided

SUBMITTER: Soomro QH 

PROVIDER: S-EPMC9528263 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature