Molecular characterization of SARS-CoV-2 from the saliva of patients in the Republic of Korea in 2020.

ABSTRACT:

Background and aims

Despite global vaccination efforts, the number of confirmed cases of coronavirus disease 2019 (COVID-19) remains high. To overcome the crisis precipitated by the ongoing pandemic, characteristic studies such as virus diagnosis, isolation, and genome analysis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are necessary. Herein, we report the isolation and molecular characterization of SARS-CoV-2 from the saliva of patients who had tested positive for COVID-19 at Proving Ground in Taean County, Republic of Korea, in 2020.

Methods

We analyzed the whole-genome sequence of SARS-CoV-2 isolated from the saliva samples of patients through next-generation sequencing. We also successfully isolated SARS-CoV-2 from the saliva samples of two patients

SUBMITTER: Gu SH 

PROVIDER: S-EPMC9528954 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature