Impact and cost-effectiveness of rotavirus vaccination in Niger: a modelling study evaluating alternative rotavirus vaccines.

ABSTRACT:

Objectives

To evaluate the cost-effectiveness of alternative rotavirus vaccines in Niger, using UNIVAC, a proportionate outcomes model.

Setting

The study leverages global, regional and local data to inform cost-effectiveness modelling. Local data were collected as part of a clinical trial taking place in the Madarounfa district, Maradi region, Niger.

Participants

The study models impact of infants vaccination on rotavirus gastroenteritis in children under 5 years of age.

Interventions

We compared the use of ROTARIX (GlaxoSmithKline, Belgium), ROTAVAC (Bharat Biotech, India) and ROTASIIL (Serum Institute, India) to no vaccination and to each other over a 10-year period starting in 2021.

Results

We estimated that ROTARIX, ROTAVAC and ROTASIIL would each pr

SUBMITTER: Debellut F 

PROVIDER: S-EPMC9535195 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature