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Building an integrated serosurveillance platform to inform public health interventions: Insights from an experts' meeting on serum biomarkers.


ABSTRACT: The use of biomarkers to measure immune responses in serum is crucial for understanding population-level exposure and susceptibility to human pathogens. Advances in sample collection, multiplex testing, and computational modeling are transforming serosurveillance into a powerful tool for public health program design and response to infectious threats. In July 2018, 70 scientists from 16 countries met to perform a landscape analysis of approaches that support an integrated serosurveillance platform, including the consideration of issues for successful implementation. Here, we summarize the group's insights and proposed roadmap for implementation, including objectives, technical requirements, ethical issues, logistical considerations, and monitoring and evaluation.

SUBMITTER: Wiens KE 

PROVIDER: S-EPMC9536637 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature

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Building an integrated serosurveillance platform to inform public health interventions: Insights from an experts' meeting on serum biomarkers.

Wiens Kirsten E KE   Jauregui Barbara B   Arnold Benjamin F BF   Banke Kathryn K   Wade Djibril D   Hayford Kyla K   Costero-Saint Denis Adriana A   Hall Robert H RH   Salje Henrik H   Rodriguez-Barraquer Isabel I   Azman Andrew S AS   Vernet Guy G   Leung Daniel T DT  

PLoS neglected tropical diseases 20221006 10


The use of biomarkers to measure immune responses in serum is crucial for understanding population-level exposure and susceptibility to human pathogens. Advances in sample collection, multiplex testing, and computational modeling are transforming serosurveillance into a powerful tool for public health program design and response to infectious threats. In July 2018, 70 scientists from 16 countries met to perform a landscape analysis of approaches that support an integrated serosurveillance platfo  ...[more]

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