Hypoallergenicity assessment of an extensively hydrolyzed whey-protein formula in cow's milk allergic infants.

ABSTRACT:

Background

Extensively hydrolyzed formulas are recommended for the dietary management of infants with cow's milk allergy (CMA).

Objectives

Hypoallergenicity, growth, and gastrointestinal (GI) tolerability of a new extensively hydrolyzed whey-protein formula (eHWF) in CMA children were assessed.

Methods

In this prospective, randomized, international, multi-center study (Trial NL3889), 34 children with confirmed CMA (74% IgE-mediated) underwent a double-blind, placebo-controlled food challenge (DBPCFC) with an eHWF developed with non-porcine enzymes, supplemented with prebiotic short-chain galacto- and long-chain fructo-oligosaccharides (0.8 g/L, ratio 9:1), arachidonic acid (0.35/100 g), and docosahexaenoic acid (0.35/100 g). If tolerant to the eHWF, children participa

SUBMITTER: Dahdah L 

PROVIDER: S-EPMC9542408 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature