Evaluating hop extract concentrations found in commercial beer to inhibit Streptococcus mutans biofilm formation.

ABSTRACT:

Aims

The purpose of this study was to compare the effect of hop extracts with diverse β-acid concentrations on Streptococcus mutans biofilm formation.

Methods and results

Ten different hop extracts, with α-acid concentrations similar to those found in commercial beer products and β-acid concentrations ranging from 2.6 to 8.1%, were added to distilled water to make standardized concentrations. S. mutans isolates were treated with hop extract dilutions varying from 1:2 to 1:256. The minimum inhibitory, minimum bactericidal and minimum biofilm inhibitory concentrations were determined and the optical density was evaluated. Live/dead staining confirmed the bactericidal effects. Biofilm formation of several strains of S. mutans was significantly inhibited by hop extract dilutions

SUBMITTER: Gregory ER 

PROVIDER: S-EPMC9543398 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature