Sodium supply from administered blood products was associated with severe intraventricular haemorrhage in extremely preterm infants.

ABSTRACT:

Aim

The aim of this study was to investigate the associations between sodium supply, fluid volume, sodium imbalances and severe intraventricular haemorrhage (IVH) in extremely preterm (EPT) infants.

Methods

We used data from the EXtremely PREterm infants in Sweden Study (EXPRESS) cohort consisting of all infants born at 22 to 26 gestational weeks from 2004 to 2007 and conducted a nested case-control study. For every infant with severe IVH (grade 3 or peri-ventricular haemorrhagic infarction), one IVH-free control infant with the birthday closest to the case infant and matched for hospital, sex, gestational age and birth weight was selected (n = 70 case-control pairs).

Results

Total sodium supply and fluid volume were higher in infants with severe IVH compared with con

SUBMITTER: Spath C 

PROVIDER: S-EPMC9543447 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature