Posterior uveal melanoma incidence and survival by AJCC tumour size in a 70-year nationwide cohort.

ABSTRACT:

Purpose

While early treatment of posterior uveal melanoma can save the eye, the effect of early treatment on survival remains unknown. Therefore, we aimed to determine whether the tumour size at diagnosis has changed over time, and if this has affected survival rates of patients with posterior uveal melanoma in Denmark.

Methods

Nationwide retrospective cohort study linking data from registry-based resources to data from clinical charts and pathology records. Including all Danish patients diagnosed with posterior uveal melanoma from 1943 to 2017. Incidence rates were estimated as annual percentage change (APC) overall and by American Joint Committee on Cancer (AJCC) tumour sizes. The age-period-cohort model was applied to estimate the relative risk of calendar period. The cox

SUBMITTER: Smidt-Nielsen I 

PROVIDER: S-EPMC9543793 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature