Ethnic disparities in liver fat accumulation in school-aged children.

ABSTRACT:

Objective

Nonalcoholic fatty liver disease (NAFLD) has a different prevalence in adults from different ethnic groups. This study examined whether these ethnic differences originate in early life and could be explained by early-life factors.

Methods

This observational study was embedded in a population-based prospective cohort study from fetal life onward among 2,570 children born in Rotterdam, the Netherlands. Information about prepregnancy, pregnancy, and childhood factors, as well as childhood BMI, was obtained from questionnaires and physical examinations. Liver fat was assessed by magnetic resonance imaging at age 10 years.

Results

Median liver fat fraction was 2.0% (95% CI: 1.2%-5.3%), and NAFLD prevalence was 2.8%. Children from a Turkish background had the high

SUBMITTER: de Groot JM 

PROVIDER: S-EPMC9546249 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature