Is repeated childhood fracture related to areal bone density or body composition in middle age?

ABSTRACT: Childhood fracture is common, but whether it predicts adult fracture is not clear. Repeat childhood fracture was associated with adult (≤ 45 years) fracture, and in women, lower areal bone density was associated with repeat childhood fracture. Identifying fracture-prone children can modify adult fracture risk management.

Introduction

A quarter of boys and 15% of girls will suffer multiple fractures, but it is not clear whether multiple fractures during growth predict fracture risk and areal bone density in adulthood. This study evaluated whether children who repeatedly fracture were at increased risk of low areal bone density, abnormal body composition, and fractures by age 45.

Methods

A subsample of a large birth cohort study with childhood fracture cases had areal bone dens

SUBMITTER: Kim MJ 

PROVIDER: S-EPMC9568436 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature