Association of Glycosylated Hemoglobin Level and Cancer-Related Mortality in Patients without Diabetes.

ABSTRACT:

Background

Previous studies have reported that abnormal glucose metabolism is associated with poor cancer outcomes. Glycated hemoglobin A1c (HbA1c) is an important indicator of glucose metabolism. This study aimed to investigate the relationship between nondiabetic HbA1c levels and cancer-related mortality.

Methods

This was a retrospective cohort study of Koreans who attended an annual or biennial health checkup program. The study group was categorized based on the quintile of HbA1c level (Q1, 3.0-5.1%; Q2, 5.2-5.3%; Q3, 5.4%; Q4, 5.5-5.6%, Q5, 5.7-6.4%). Cancer-related mortality was determined using the mortality data from the Korea National Statistical Office. Participants with an established diagnosis of diabetes or cancer were excluded. Cancer-related mortality was asses

SUBMITTER: Yoo TK 

PROVIDER: S-EPMC9570990 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature