Association of mRNA Vaccination With Clinical and Virologic Features of COVID-19 Among US Essential and Frontline Workers.

ABSTRACT:

Importance

Data on the epidemiology of mild to moderately severe COVID-19 are needed to inform public health guidance.

Objective

To evaluate associations between 2 or 3 doses of mRNA COVID-19 vaccine and attenuation of symptoms and viral RNA load across SARS-CoV-2 viral lineages.

Design, setting, and participants

A prospective cohort study of essential and frontline workers in Arizona, Florida, Minnesota, Oregon, Texas, and Utah with COVID-19 infection confirmed by reverse transcriptase-polymerase chain reaction testing and lineage classified by whole genome sequencing of specimens self-collected weekly and at COVID-19 illness symptom onset. This analysis was conducted among 1199 participants with SARS-CoV-2 from December 14, 2020, to April 19, 2022, with follow-up un

SUBMITTER: HEROES-RECOVER Network 

PROVIDER: S-EPMC9579910 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature