Recapitulation of the embryonic transcriptional program in holometabolous insect pupae.

ABSTRACT: Holometabolous insects are predominantly motionless during metamorphosis, when no active feeding is observed and the body is enclosed in a hardened cuticle. These physiological properties as well as undergoing processes resemble embryogenesis, since at the pupal stage organs and systems of the imago are formed. Therefore, recapitulation of the embryonic expression program during metamorphosis could be hypothesized. To assess this hypothesis at the transcriptome level, we have performed a comprehensive analysis of the developmental datasets available in the public domain. Indeed, for most datasets, the pupal gene expression resembles the embryonic rather than the larval pattern, interrupting gradual changes in the transcriptome. Moreover, changes in the transcriptome profile during the pupa

SUBMITTER: Ozerova AM 

PROVIDER: S-EPMC9584902 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature