Pre-vaccination RT-PCR negative contacts in workplace settings show high, SARS COV-2 neutralizing antibody levels.

ABSTRACT:

Background

Asymptomatic SARS-CoV-2 infection occurring in RT-PCR negative individuals represent a poorly characterized cohort with important infection control connotations. While household and community-based studies have evaluated seroprevalence of antibody and transmission dynamics in this group, workplace-based data is currently unavailable.

Methods

A cohort study was carried out in July 2021, during and immediately following the peak of the 3^rd wave of COVID-19 in Sri Lanka, prior to mass vaccination. A total of 92 unvaccinated individuals between the ages of 17-65 years were purposively sampled from an office and two factory settings. The selected cohort that had been exposed to RT-PCR positive cases in the workplace was tested RT-PCR negative. Serological sa

SUBMITTER: Karunathilake RP 

PROVIDER: S-EPMC9593990 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature