COVID-19 Severity and Thrombo-Inflammatory Response Linked to Ethnicity.

ABSTRACT: Although there is strong evidence that SARS-CoV-2 infection is associated with adverse outcomes in certain ethnic groups, the association of disease severity and risk factors such as comorbidities and biomarkers with racial disparities remains undefined. This retrospective study between March 2020 and February 2021 explores COVID-19 risk factors as predictors for patients' disease progression through country comparison. Disease severity predictors in Germany and Japan were cardiovascular-associated comorbidities, dementia, and age. We adjusted age, sex, body mass index, and history of cardiovascular disease comorbidity in the country cohorts using a propensity score matching (PSM) technique to reduce the influence of differences in sample size and the surprisingly young, lean Japanese coho

SUBMITTER: Heissig B 

PROVIDER: S-EPMC9599040 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature