Ontology highlight
ABSTRACT:
SUBMITTER: Takasawa S
PROVIDER: S-EPMC9603944 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Takasawa Shin S Itaya-Hironaka Asako A Makino Mai M Yamauchi Akiyo A Sakuramoto-Tsuchida Sumiyo S Uchiyama Tomoko T Shobatake Ryogo R Takeda Yoshinori Y Ota Hiroyo H
International journal of molecular sciences 20221017 20
Sleep apnea syndrome (SAS) is characterized by recurrent episodes of oxygen desaturation and reoxygenation (intermittent hypoxia [IH]), and is a risk factor for cardiovascular disease (CVD) and insulin resistance/Type 2 diabetes. However, the mechanisms linking IH stress and CVD remain elusive. We exposed rat H9c2 and mouse P19.CL6 cardiomyocytes to experimental IH or normoxia for 24 h to analyze the mRNA expression of several cardiomyokines. We found that the mRNA levels of regenerating gene IV ...[more]