Feasibility of transcutaneous spinal direct current stimulation combined with locomotor training after spinal cord injury.

ABSTRACT:

Study design

Feasibility study, consisting of random-order, cross-over study of a single intervention session, followed by a parallel-arm study of 16 sessions.

Objectives

To investigate the feasibility of a novel combinatorial approach with simultaneous delivery of transcutaneous spinal direct current stimulation (tsDCS) and locomotor training (tsDCS + LT) after spinal cord injury, compared to sham stimulation and locomotor training (sham + LT), and examine preliminary effects on walking function.

Setting

Clinical research center in the southeastern United States.

Methods

Eight individuals with chronic incomplete spinal cord injury (ISCI) completed the two-part protocol. Feasibility was assessed based on safety (adverse responses), tolerability (pain, spasticit

SUBMITTER: Hawkins KA 

PROVIDER: S-EPMC9606142 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature