Ontology highlight
ABSTRACT:
SUBMITTER: Xie LY
PROVIDER: S-EPMC9609457 | biostudies-literature | 2022 Oct
REPOSITORIES: biostudies-literature
Molecules (Basel, Switzerland) 20221019 20
An efficient and straightforward approach for the synthesis of carbamoylated chroman-4-ones has been well-developed. The reaction is triggered through the generation of carbamoyl radicals from oxamic acids under metal-free conditions, which subsequently undergoes decarboxylative radical cascade cyclization on 2-(allyloxy)arylaldehydes to afford various amide-containing chroman-4-one scaffolds with high functional group tolerance and a broad substrate scope. ...[more]