Phylogeography of Rotavirus G8P[8] Detected in Argentina: Evidence of Transpacific Dissemination.

ABSTRACT: Rotavirus is one of the leading causes of diarrhea in children. In 2018, G8P[8], an unusual association of genotypes, was detected with moderate frequency in symptomatic children in Argen-tina, unlike a previous sporadic identification in 2016. The aim of this study was to analyze the dissemination pattern of the G8P[8]-lineage IV strains detected in Argentina. Nucleotide sequences of the VP7 gene of Argentine G8P[8] strains (2016, 2018 and 2019) were studied by discrete phylodynamic analyses, together with other worldwide relevant G8-lineage IV strains. Bayes Factor (BF) was used to assess the strength of the epidemiological association between countries. Phylodynamic analyses determined an evolutionary rate of 3.7 × 10^-3 (HDP95%: 1.4 × 10^-3-8.2 × 10^-3) su

SUBMITTER: Degiuseppe JI 

PROVIDER: S-EPMC9609476 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature