Bioactive compounds as potential angiotensin-converting enzyme II inhibitors against COVID-19: a scoping review.

ABSTRACT:

Objective and design

The current study aimed to summarize the evidence of compounds contained in plant species with the ability to block the angiotensin-converting enzyme 2 (ACE-II), through a scoping review.

Methods

PubMed and Scopus electronic databases were used for the systematic search and a manual search was performed RESULTS: Studies included were characterized as in silico. Among the 200 studies retrieved, 139 studies listed after the exclusion of duplicates and 74 were included for the full read. Among them, 32 studies were considered eligible for the qualitative synthesis. The most evaluated class of secondary metabolites was flavonoids with quercetin and curcumin as most actives substances and terpenes (isothymol, limonin, curcumenol, anabsinthin, and artemisinin)

SUBMITTER: de Matos PH 

PROVIDER: S-EPMC9616414 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature