Trimester-specific prenatal heavy metal exposures and sex-specific postpartum size and growth.

ABSTRACT:

Background

There has been limited research considering the effects of prenatal exposure to multiple heavy metals on early childhood size and growth.

Objective

We evaluated prenatal exposures to 15 heavy metals in association with measures of weight, length, and head circumference (HC) measured at birth, and 1, 3 and 6 months of age in a study of 358 mother-child pairs.

Methods

Urinary concentrations were measured in the first and third trimesters of pregnancy and examined, using sex-stratified general linear models, in association with average standardized size and changes in size (growth) over the first 6 months of life. Confounding effects among metals were explored.

Results

Increased first trimester Hg and V were associated with decreased average HC among ma

SUBMITTER: Yao L 

PROVIDER: S-EPMC9617807 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature