Macrocyclic Triazolopeptoids: A Promising Class of Extended Cyclic Peptoids.

ABSTRACT: Head-to-tail cyclization of linear oligoamides containing 4-benzylaminomethyl-1H-1,2,3-triazol-1-yl acetic acid monomers afforded a novel class of "extended macrocyclic peptoids". The identification of the conformation in solution for a cyclodimer and the X-ray crystal structure of a cyclic tetraamide are reported.

SUBMITTER: Araszczuk AM 

PROVIDER: S-EPMC9623583 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature