The association between parenteral nutrition and pancreatic injury in adult patients: a retrospective observational study.

ABSTRACT:

Background and objective

Patients on parenteral nutrition (PN) are at high risk of both liver and pancreatic injury. More efforts were focused on liver, however, limited data is available to evaluate the effects of PN on pancreas. Thus, we performed a retrospective observational study to evaluate the association between PN and pancreatic injury in Chinese adult patients.

Methods

Adult patients (18-80 years), who received PN for a week or longer, and with repeated measurements of pancreatic enzymes, were included in the analysis. Pancreatic injury was confirmed by serum level of pancreatic amylase (P-AMYwas 53 U/L or higher) or lipase (LP was 63 U/L or higher), which were evaluated at baseline and following every week during PN duration. Age, sex, body weight, height, diagnos

SUBMITTER: Zhang XM 

PROVIDER: S-EPMC9624056 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature