Contributions of early-life cognitive reserve and late-life leisure activity to successful and pathological cognitive aging.

ABSTRACT:

Background

The identification of factors that specifically influence pathological and successful cognitive aging is a prerequisite for implementing disease prevention and promoting successful aging. However, multi-domain behavioral factors that characterize the difference between successful and pathological cognitive aging are not clear yet.

Methods

A group of community-dwelling older adults (N = 1347, aged 70-88 years) in Beijing was recruited in this cross-sectional study, and a sub-cohort was further divided into successful cognitive aging (SCA, N = 154), mild cognitive impairment (MCI, N = 256), and cognitively normal control (CNC, N = 173) groups. Analyses of variance, regression models with the Shapley value algorithm, and structural equation model (SEM) analyses were

SUBMITTER: Yang Y 

PROVIDER: S-EPMC9628084 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature