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Lack of evidence of viability and infectivity of SARS-CoV-2 in the fecal specimens of COVID-19 patients.

ABSTRACT: SARS-CoV-2 can be shed in feces and can enter sewage systems. In order to implement effective control measures and identify new channels of transmission, it is essential to identify the presence of infectious virus particles in feces and sewage. In this study, we attempt to utilize Molecular techniques, cell cultures and animal models to find out the infectivity of SARS-CoV-2 in the feces of COVID-19 patients. Our findings exclude the presence of infectious virus particles, suggesting that fecal-oral transmission may not be the main mode of transmission. Larger-scale initiatives are nevertheless required, particularly considering the emergence of new viral strains.

SUBMITTER: Joshi M

PROVIDER: S-EPMC9632423 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature

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Lack of evidence of viability and infectivity of SARS-CoV-2 in the fecal specimens of COVID-19 patients.

Joshi Madhuri M Mohandas Sreelekshmy S Prasad Sharda S Shinde Manohar M Chavan Nutan N Yadav Pragya D PD Lavania Mallika M

Frontiers in public health 20221020

SARS-CoV-2 can be shed in feces and can enter sewage systems. In order to implement effective control measures and identify new channels of transmission, it is essential to identify the presence of infectious virus particles in feces and sewage. In this study, we attempt to utilize Molecular techniques, cell cultures and animal models to find out the infectivity of SARS-CoV-2 in the feces of COVID-19 patients. Our findings exclude the presence of infectious virus particles, suggesting that fecal ...[more]

PMID: 36339137

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