Investigation of the effects of quercetin and xenograft on the healing of bone defects: An experimental study.

ABSTRACT:

Objective

In this study, it was aimed to histologic and immunohistochemical examined that the effects of quercetin on new bone formation and bone regeneration in critical size rat tibial bone defects.

Material & methods

In the study, 56 rats were divided into 4 groups with 14 rats in each group. Control (C) (n = 14): A defect was created in the corticocancellous bone in the metaphyseal part of the tibia bones of the rats and no additional procedure was applied until the end of the experimental setup. Xenograft (X) group (n = 14): Bone defects were created in the tibia bones of the rats and the defects were filled with xenograft. No additional process was applied until the end of the experimental setup. Quercetin (Q) group (n = 14): A defect was created in the tibia bones of

SUBMITTER: Durmaz B 

PROVIDER: S-EPMC9636472 | biostudies-literature | 2023 Jan-Feb

REPOSITORIES: biostudies-literature