Presence of Geriatric Conditions Is Prognostic of Major Bleeding in Older Patients with Atrial Fibrillation: a Cohort Study.

ABSTRACT:

Background

In older patients with atrial fibrillation (AF), physical, cognitive, and psychosocial limitations are prevalent. The prognostic value of these conditions for major bleeding is unclear.

Objective

To determine whether geriatric conditions are prospectively associated with major bleeding in older patients with AF on anticoagulation.

Design

Multicenter cohort study with 2-year follow-up from 2016 to 2020 in Massachusetts and Georgia from cardiology, electrophysiology, and primary care clinics.

Participants

Diagnosed with AF, age 65 years or older, CHA₂DS₂-VASc score of 2 or higher, and taking oral anticoagulant (n=1,064). A total of 6507 individuals were screened.

Main measures

A six-component geriatric assessment of frailty

SUBMITTER: Wang W 

PROVIDER: S-EPMC9640487 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature