Ontology highlight
ABSTRACT:
SUBMITTER: Mun JY
PROVIDER: S-EPMC9640638 | biostudies-literature | 2022 Nov
REPOSITORIES: biostudies-literature
Mun Jeong-Yeon JY Baek Seung-Woo SW Jeong Mi-So MS Jang In-Hwan IH Lee Se-Ra SR You Jae-Young JY Kim Jeong-Ah JA Yang Gi-Eun GE Choi Yung-Hyun YH Kim Tae-Nam TN Chu In-Sun IS Leem Sun-Hee SH
Cell death discovery 20221107 1
Chemotherapy resistance is an obstacle to cancer therapy and is considered a major cause of recurrence. Thus, understanding the mechanisms of chemoresistance is critical to improving the prognosis of patients. Here, we have established a stepwise gemcitabine-resistant T24 bladder cancer cell line to understand the molecular mechanisms of chemoresistance within cancer cells. The characteristics of the stepwise chemoresistance cell line were divided into 4 phases (parental, early, intermediate, an ...[more]