Plasma acylcarnitine and diabetic retinopathy: A study from Eastern China.

ABSTRACT:

Background and purpose

Acylcarnitines (ACars) are important for insulin resistance and type 2 diabetes (T2D). However, their roles in diabetic retinopathy (DR) remain controversial. In this study, we aimed to investigate the association of ACars with DR and their values in DR detection.

Methods

This was a two-center case-control study based on the propensity score matching approach between August 2017 to June 2018 in Eastern China. Multivariable logistic regression models were applied to estimate the association of plasma ACars with DR. Differential ACars were screened by models of least absolute shrinkage and selection operator, elastic net, and weighted quantile sum regression, and their roles in DR identification were further evaluated by the area under the receiver opera

SUBMITTER: Jin D 

PROVIDER: S-EPMC9646944 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature