Conductometric and Fluorescence Probe Analysis to Investigate the Interaction between Bioactive Peptide and Bile Salts: A Micellar State Study.

ABSTRACT: The present work deals with the micellar state study of sodium cholate and sodium deoxycholate in the aqueous solution of a bioactive peptide, namely glycyl dipeptide, having different concentrations through conductivity and fluorescence methods at different temperatures. The data obtained from conductivity is plotted against the concentration of Bile salts, and CMC (critical micelle concentration) values are calculated. The results realized have been elucidated with reference to Glycyl dipeptide-bile salts hydrophobic/hydrophilic interactions existing in solution. In addition, the CMC values converted to mole fraction (Xcmc) values have been used to evaluate the standard thermodynamic factors of micellization viz., enthalpy H, free energy ΔGm0, and entropy (ΔSm0) which extra

SUBMITTER: Kumari S 

PROVIDER: S-EPMC9654833 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature