Glycemic and Insulinemic Responses of Healthy Humans to a Nutrition Bar with or without Added Fibersym^® RW, a Cross-Linked Phosphorylated RS4-Type Resistant Wheat Starch.

ABSTRACT: The current study compared postprandial glycemic and insulinemic responses to four nutrition bars containing two different doses of resistant starch type-4. Normoglycemic adults (n = 17) completed six treatments, consuming either 50 g or 30 g digestible carbohydrate as: dextrose beverages (DEX), control puffed wheat bars (PWB), or RS4 test bars (RS4). Glucose (mg/dL) and insulin (µIU/mL) were measured at baseline and 10, 20, 30, 60, 90, and 120 min. There was a main effect of dose and treatment on glucose incremental area under the curve (iAUC, ps < 0.001), such that RS4 (50 g: 941, 95% confidence interval (CI): 501, 1519; 30 g: 481, 95% CI: 186, 914) was lower than PWB (50 g: 1746, 95% CI: 1109, 2528; 30 g: 693, 95% CI: 331, 1188) and DEX (50 g: 1940, 95% CI: 1249, 2783;

SUBMITTER: Steele TJ 

PROVIDER: S-EPMC9654973 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature