Anti-HSV Activity of Metallic Nanoparticles Functionalized with Sulfonates vs. Polyphenols.

ABSTRACT: Metallic nanoparticles exhibit broad-spectrum activity against bacteria, fungi, and viruses. The antiviral activity of nanoparticles results from the multivalent interactions of nanoparticles with viral surface components, which result from the nanometer size of the material and the presence of functional compounds adsorbed on the nanomaterial surface. A critical step in the virus infection process is docking and entry of the virus into the host cell. This stage of the infection can be influenced by functional nanomaterials that exhibit high affinity to the virus surface and hence can disrupt the infection process. The affinity of the virus to the nanomaterial surface can be tuned by the specific surface functionalization of the nanomaterial. The main purpose of this work was to determine

SUBMITTER: Tomaszewska E 

PROVIDER: S-EPMC9657688 | biostudies-literature | 2022 Oct

REPOSITORIES: biostudies-literature